References: Drugs associated with the development of takotsubo

Drugs associated with the development of takotsubo

Cardiotonic drugs

¹ Redfors, B., Ali, A., Shao, Y., Lundgren, J., Gan, L.M. and Omerovic, E., 2014. Different catecholamines induce different patterns of takotsubo-like cardiac dysfunction in an apparently afterload dependent manner. International Journal of Cardiology, 174(2), pp.330-336.

Adrenalin/norarenalin
²Kido, K. and Guglin, M., 2017. Drug-induced takotsubo cardiomyopathy. Journal of Cardiovascular Pharmacology and Therapeutics, 22(6), pp.552-563. https://doi.org/10.1177/1074248417708618
³Nazir, S., Lohani, S., Tachamo, N., Ghimire, S., Poudel, D.R. and Donato, A., 2017. Takotsubo cardiomyopathy associated with epinephrine use: a systematic review and meta-analysis. International Journal of Cardiology, 229, pp.67-70. https://doi.org/10.1016/j.ijcard.2016.11.266
⁴Y-Hassan, Shams 2017. Serotonin norepinephrine re-uptake inhibitor (SNRI)-, selective norepinephrine reuptake inhibitor (S-NRI)-, and exogenously administered norepinephrine-induced takotsubo syndrome: Analysis of published cases. International journal of cardiology, 231, pp.228-233. https://doi.org/10.1016/j.ijcard.2016.12.184
⁵Fyfe, A.I., Daly, P.A., Dorian, P. and Tough, J., 1991. Reversible “cardiomyopathy” after accidental adrenaline overdose. The American journal of cardiology, 67(4), pp.318-319. DOI:10.1016/0002-9149(91)90570-B
⁶Budhwani, N., Bonaparte, K.L., Cuyjet, A.B. and Saric, M., 2004. Severe reversible left ventricular systolic and diastolic dysfunction due to accidental iatrogenic epinephrine overdose. Reviews in cardiovascular medicine, pp.130-133.  https://pdfs.semanticscholar.org/9976/e3fc0bda8af038cac1a26cf916749681f224.pdf
⁷Meaudre, E., Barbou, F., Sallaberry, M., Cantais, E., Petit, D. and Palmier, B., 2004. Rapid reversal of global left ventricular dysfunction after accidental injection of 0.75 mg epinephrine in a 20‐year‐old patient. Acta anaesthesiologica scandinavica, 48(7), pp.914-916.
⁸Volz, H.C., Erbel, C., Berentelg, J., Katus, H.A. and Frey, N., 2009. Reversible left ventricular dysfunction resembling Takotsubo syndrome after self-injection of adrenaline. The Canadian Journal of Cardiology, 25(7), p.e261.
⁹Abraham, J., Mudd, J.O., Kapur, N., Klein, K., Champion, H.C. and Wittstein, I.S., 2009. Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. Journal of the American College of Cardiology, 53(15), pp.1320-1325. doi:10.1016/j.jacc.2009.02.02
¹⁰Härle, T., Kronberg, K., Nef, H., Möllmann, H. and Elsässer, A., 2011. Inverted Takotsubo cardiomyopathy following accidental intravenous administration of epinephrine in a young woman. Clinical Research in Cardiology, 100(5), pp.471-473. https://doi.org/ 10.1007/s00392-010-0266-z
¹¹Esnault, P., Née, L., Signouret, T., Jaussaud, N. and Kerbaul, F., 2014. Reverse Takotsubo cardiomyopathy after iatrogenic epinephrine injection requiring percutaneous extracorporeal membrane oxygenation. Canadian Journal of Anesthesia/Journal Canadien d’Anesthésie, 61(12), pp.1093-1097. https://doi.org/ 10.1007/s12630-014-0230-x
¹²Sherif, K., Sehli, S. and Jenkins, L.A., 2016, April. Takotsubo cardiomyopathy after administration of norepinephrine. In Baylor University Medical Center Proceedings (Vol. 29, No. 2, pp. 166-167). Taylor & Francis. https://doi.org/ 10.1080/08998280.2016.11929402
¹³Ouerghi, K., Boukhris, M., Grall, S., Desprets, L. and Quercy, M., 2016. Reverse iatrogenic Takotsubo syndrome after accidental bolus of norepinephrine in the setting of sepsis. Kardiologia Polska (Polish Heart Journal), 74(8), pp.799-799.
¹⁴Subramaniam, A., Cooke, J.C. and Ernest, D., 2010. ‘Inverted’ Tako-Tsubo Cardiomyopathy Due to Exogenous Catecholamines. Critical Care and Resuscitation, 12(2), p.104.
¹⁵Keshtkar, F., Dale, O.T., Bennett, W.O. and Hall, C.E., 2016. Management of airway obstruction with nebulised adrenaline resulting in takotsubo cardiomyopathy: case report. The Journal of Laryngology & Otology, 130(9), pp.883-886. https://doi.org/10.1017/S0022215116008288
¹⁶Zubrinich, C.M., Omar Farouque, H.M., Rochford, S.E. and Sutherland, M.F., 2008. Tako‐tsubo‐like cardiomyopathy after EpiPen administration. Internal
medicine journal, 38(11), pp.862-865. https://doi.org/10.1111/j.1445-5994.2008.01748.x
¹⁷Litvinov, I.V., Kotowycz, M.A. and Wassmann, S., 2009. Iatrogenic epinephrine-induced reverse Takotsubo cardiomyopathy: direct evidence supporting the role of catecholamines in the pathophysiology of the “broken heart syndrome”. Clinical research in cardiology, 98(7), pp.457-462. https://doi.org/ 10.1007/s00392-009-0028-y
¹⁸Manivannan, V., Li, J.T., Prasad, A. and Campbell, R.L., 2009, September. Apical ballooning syndrome after administration of intravenous epinephrine during an anaphylactic reaction. In Mayo Clinic Proceedings (Vol. 84, No. 9, p. 845). Mayo Foundation.
¹⁹Laínez, B., Ureña, M., Álvarez, V. and Lezaun, R., 2009. Iatrogenic Tako–Tsubo Cardiomyopathy Secondary to Catecholamine Administration. Revista espanola de cardiologia, 62(12), p.1498. DOI:10.1016/S1885-5857(09)73549-2
²⁰Geppert, G., Radke, P.W., Kurowski, V., Hunold, P. and Schunkert, H., 2010. Wasp sting, adrenaline injection and acute thoracic pain: an un usual case of stress-induced (tako-tsubo) cardiomyopathy. Medizinische Klinik (Munich, Germany: 1983), 105(4), pp.246-248. https://doi.org/ 10.1007/s00063-010-1032-8
²¹Morel, O., Jesel, L., Morel, N., Nguyen, A., Trinh, A., Ohlmann, P. and Imperiale, A., 2010. Transient left ventricular dysfunction syndrome during anaphylactic shock: vasospasm, Kounis syndrome or epinephrine-induced stunned myocardium?. International journal of cardiology, 145(3), pp.501-503.
²²Dewachter, P., Tanase, C., Levesque, E., Nicaise-Roland, P., Chollet-Martin, S., Mouton-Faivre, C. and Benhamou, D., 2011. Apical ballooning syndrome following perioperative anaphylaxis is likely related to high doses of epinephrine. Journal of anesthesia, 25(2), pp.282-285. https://doi.org/10.1007/s00540-010-1085-0
²³Magri, C.J., Fava, S. and Felice, H., 2011. Inverted takotsubo cardiomyopathy secondary to adrenaline injection. British Journal of Hospital Medicine, 72(11), pp.646-647. https://doi.org/10.12968/hmed.2011.72.11.646
²⁴Scheiba, N., Viedt-Suelmann, C. and Schäkel, K., 2011. Tako-tsubo cardiomyopathy after a hymenoptera sting and treatment with catecholamines. Acta dermato-venereologica, 91(5), pp.593-594. https://doi.org/10.2340/00015555-1119
²⁵Winogradow, J., Geppert, G., Reinhard, W., Resch, M., Radke, P.W. and Hengstenberg, C., 2011. Tako-tsubo cardiomyopathy after administration of intravenous epinephrine during an anaphylactic reaction. International Journal of Cardiology, 147(2), pp.309-311. https://doi.org/10.1016/j.ijcard.2010.12.063
²⁶Patankar, G.R., Donsky, M.S. and Schussler, J.M., 2012. Delayed takotsubo cardiomyopathy caused by excessive exogenous epinephrine administration after the treatment of angioedema. Proceedings (Baylor University. Medical Center), 25(3), p.229.
²⁷Kajander, O.A., Virtanen, M.P., Sclarovsky, S. and Nikus, K.C., 2013. Iatrogenic inverted takotsubo syndrome following intravenous adrenaline injections for an allergic reaction. International journal of cardiology, 165(1), pp.e3-e5. https://doi.org/10.1016/j.ijcard.2012.09.157
²⁸Khoueiry, G., Rafeh, N.A., Azab, B., Markman, E., Waked, A., AbouRjaili, G., Shariff, M. and Costantino, T., 2013. Reverse Takotsubo cardiomyopathy in the setting of anaphylaxis treated with high-dose intravenous epinephrine. The Journal of emergency medicine, 44(1), pp.96-99. https://doi.org/10.1016/j.jemermed.2011.09.032
²⁹Ghanim, D., Adler, Z., Qarawani, D., Kusniec, F., Amir, O. and Carasso, S., 2015. Takotsubo cardiomyopathy caused by epinephrine-treated bee sting anaphylaxis: a case report. Journal of medical case reports, 9(1), p.247. https://doi.org/10.1186/s13256-015-0722-5
³⁰Surineni, K., Afzal, M.R., Barua, R. and Parashara, D., 2016. Epinephrine-Induced Takotsubo Cardiomyopathy. Federal Practitioner. October. https://mdedge-files-live.s3.us-east-2.amazonaws.com/files/s3fs-public/1016FP_Parashara.PDF
³¹Saeki, S., Matsuse, H., Nakata, H., Fukahori, S., Miyahara, Y. and Kohno, S., 2006. Case of bronchial asthma complicated with Takotsubo cardiomyopathy after frequent epinephrine medication. Nihon Kokyuki Gakkai zasshi= the journal of the Japanese Respiratory Society, 44(10), pp.701-705.
³²Copetti, R., Gonano, C., Colombo, T. and Cattarossi, L., 2007. “Inverted Takotsubo” pattern. Resuscitation, 74(2), p.394. http://doi.org/ 10.1016/j.resuscitation.2007.04.009
³³Redfors, Y. Shao, E. Omerovic Fatal stress-induced cardiomyopathy in a young patient treated with adrenomimetics Clin. Res. Cardiol., 101 (2012), pp. 939-940.
³⁴Law, C., Khaliq, A. and Guglin, M., 2013. Reversible cardiogenic shock due to catecholamine-induced cardiomyopathy: a variant of takotsubo?. The American Journal of Emergency Medicine, 31(11), pp.1621-e1. https://doi.org/10.1016/j.ajem.2013.05.042
³⁵Quick, S., Quick, C., Schneider, R., Sveric, K., Katzke, S., Strasser, R.H. and Ibrahim, K., 2013. Guillain–Barré syndrome and catecholamine therapy. A potential risk for developing takotsubo cardiomyopathy?. International journal of cardiology, 165(3), pp.e43-e44. https://doi.org/10.1016/j.ijcard.2012.10.083
³⁶Vieira A, Batista B, de Abreu T. 2018. Iatrogenic Takotsubo cardiomyopathy secondary to norepinephrine by continuous infusion for shock. European Journal of Case Reports in Internal Medicine; 5 doi:10.12890/2018_000894.
³⁷Littlejohn, F.C., Syed, O., Ornstein, E., Connolly, E.S. and Heyer, E.J., 2008. Takotsubo cardiomyopathy associated with anesthesia: three case reports. Cases journal, 1(1), p.227. https://doi.org/10.1186/1757-1626-1-227
³⁸Tomcsányi, J., Arabadzisz, H., Frész, T., Sármán, B., Bózsik, B., Zsoldos, A. and Simor, T., 2008. Reverse Takotsubo syndrome pattern induced by local anaesthesia. Orvosi hetilap, 149(50), pp.2387-2389. https://doi.org/10.1556/OH.2008.28433
³⁹Harika, R., Bermas, K., Hughes, C., Al-Khafaji, A., Iyer, M. and Wallace, D.J., 2014. Cardiac arrest after liver transplantation in a patient with takotsubo cardiomyopathy. British Journal of Anaesthesia, 112(3), pp.594-595. https://doi.org/doi:10.1093/bja/aeu029
⁴⁰von Knobelsdorff-Brenkenhoff, F., Abdel-Aty, H. and Schulz-Menger, J., 2010. Takotsubo cardiomyopathy after nasal application of epinephrine—a magnetic resonance study. International journal of cardiology, 145(2), pp.308-309. https://doi.org/10.1016/j.ijcard.2009.10.044
⁴¹Rodríguez, A., Freire, L., Cerizola, M., Olivera, M., Cordobez, J. and Trujillo, P., 2012. Síndrome de takotsubo durante la inducción de una anestesia general. Anestesia Analgesia Reanimación, 25(1), pp.13-18. http://www.scielo.edu.uy/scielo.php?pid=S1688-12732012000100005&script=sci_arttext&tlng=pt
⁴²Brunetti, N.D., Ferraretti, A., Scarcia, M., Sai, R., Ieva, R., Santoro, F., De Gennaro, L. and Di Biase, M., 2013. Ultra-fast Tako-Tsubo cardiomyopathy after local anesthesia for eye surgery: Are we missing the submerged bottom of the iceberg?. International journal of cardiology, 167(5), pp.e137-e139.
⁴³Sundbøll, J., Pareek, M., Høgsbro, M. and Madsen, E.H., 2014. Iatrogenic takotsubo cardiomyopathy induced by locally applied epinephrine and cocaine. BMJ case reports, 2014, p.bcr2013202401. https://doi.org/10.1136/bcr-2013-202401.
⁴⁴Imnadze, G., Metreveli, L., Franz, N. and Thale, J., 2014. Case of Takotsubo cardiomyopathy after tooth extraction–Unusual trigger of a rare syndrome.
Journal of cardiology cases, 10(4), pp.129-131.
⁴⁵Gicquel-Schlemmer, B., Beller, J.P., Mchalwat, A. and Gicquel, P., 2015. Fatal Takotsubo cardiomyopathy due to epinephrine in shoulder arthroscopy. Orthopaedics & Traumatology: Surgery & Research, 101(8), pp.981-982. https://doi.org/10.1016/j.otsr.2015.09.026

Dobutamine and dopamine

⁴⁶Brewington, S.D., Abbas, A.A., Dixon, S.R., Grines, C.L. and O’neill, W.W., 2006. Reproducible microvascular dysfunction with dobutamine infusion in Takotsubo cardiomyopathy presenting with ST segment elevation. Catheterization and cardiovascular interventions, 68(5), pp.769-774. https://doi.org/10.1002/ccd.20514
⁴⁷Silberbauer, J., Hong, P. and Lloyd, G.W., 2007. Takotsubo cardiomyopathy (left ventricular ballooning syndrome) induced during dobutamine stress echocardiography. European Journal of Echocardiography, 9(1), pp.136-138. https://doi.org/10.1016/j.euje.2007.04.006
⁴⁸Cherian, J., Kothari, S., Angelis, D., Atef, A., Downey, B. and Kirkpatrick Jr, J., 2008. Atypical takotsubo cardiomyopathy: dobutamine-precipitated apical ballooning with left ventricular outflow tract obstruction. Texas Heart Institute Journal, 35(1), p.73.
⁴⁹Kumar, A., Jenkins, L.A., Perez-Verdia, A. and Roongsritong, C., 2008. Transient left ventricular apical ballooning during dobutamine myocardial perfusion imaging. International journal of cardiology, 124(3), pp.378-380. https://doi.org/10.1016/j.ijcard.2006.11.248
⁵⁰Bruder, O., Hunold, P., Jochims, M., Waltering, K.U., Sabin, G.V. and Barkhausen, J., 2008. Reversible late gadolinium enhancement in a case of Takotsubo cardiomyopathy following high-dose dobutamine stress MRI. International journal of cardiology, 127(1), pp.e22-e24. https://doi.org/10.1016/j.ijcard.2007.01.081
⁵¹Margey, R., Diamond, P., McCann, H. and Sugrue, D., 2008. Dobutamine stress echo-induced apical ballooning (Takotsubo) syndrome. European Journal of Echocardiography, 10(3), pp.395-399. https://doi.org/10.1093/ejechocard/jen292
⁵²Skolnick, A.H., Michelin, K., Nayar, A., Fisher, D. and Kronzon, I., 2009. Transient apical ballooning syndrome precipitated by dobutamine stress testing. Annals of internal medicine, 150(7), pp.501-502.
⁵³Abraham, J., Mudd, J.O., Kapur, N., Klein, K., Champion, H.C. and Wittstein, I.S., 2009. Stress cardiomyopathy after intravenous administration of catecholamines and beta-receptor agonists. Journal of the American College of Cardiology, 53(15), pp.1320-1325. doi:10.1016/j.jacc.2009.02.02
⁵⁴Shah, B.N., Simpson, I.A. and Rakhit, D.J., 2010. Takotsubo (apical ballooning) syndrome in the recovery period following dobutamine stress echocardiography: a first report. European Journal of Echocardiography, 12(1), pp.E5-E5. https://doi.org/10.1093/ejechocard/jeq107
⁵⁵Chaparro-Muñoz, M., Recio-Mayoral, A., Kaski, J.C., Brecker, S. and Sutherland, G.R., 2010. Myocardial stunning identified by using strain/strain rate imaging during dobutamine stress echocardiography in a rare late recurrence of Tako–Tsubo syndrome. International journal of cardiology, 145(1), pp.e9-e12. https://doi.org/10.1016/j.ijcard.2008.12.095
⁵⁶Mosley II, W.J., Manuchehry, A., McEvoy, C. and Rigolin, V., 2010. Takotsubo cardiomyopathy induced by dobutamine infusion: a new phenomenon or an old disease with a new name. Echocardiography, 27(3), pp.E30-E33. https://doi.org/10.1111/j.1540-8175.2009.01089.x
⁵⁷Arias, A.M., Oberti, P.F., Pizarro, R., Falconi, M.L., de Arenaza, D.P., Zeffiro, S. and Cagide, A.M., 2011. Dobutamine-precipitated Takotsubo cardiomyopathy mimicking acute myocardial infarction: a multimodality image approach. Circulation, 124(12), pp.e312-e315. https://doi.org/10.1161/CIRCULATIONAHA.110.008557
⁵⁸Chia, P.L. and Lee, E., 2012. Reverse Takotsubo pattern stress cardiomyopathy in a male patient induced during dobutamine stress echocardiography. Annals of the Academy of Medicine, Singapore, 41(6), pp.264-264.
⁵⁹D’Aloia, A., Caretta, G., Vizzardi, E., Zanini, G., Bugatti, S., Bonadei, I. and Dei Cas, L., 2012. Heart failure syndrome due to dobutamine stress echocardiography: Tako-Tsubo induced-cardiomiopathy. Panminerva Med, 54(1), pp.53-5.
⁶⁰Fineschi, M., D’ascenzi, F., Sirbu, V., Mondillo, S. and Pierli, C., 2013. The Role of Optical Coherence Tomography in Clarifying the Mechanisms for Dobutamine Stress Echocardiography‐Induced Takotsubo Cardiomyopathy. Echocardiography, 30(5), pp.E121-E124. 10.1111/echo.12107
⁶¹Anthony, F.Y., Mitter, S.S. and Chaudhry, H.W., 2013. Apical ballooning syndrome precipitated by dobutamine stress testing. Heart Asia, 5(1), pp.47-48. DOI: 10.1136/heartasia-2013-010292
⁶²Hajsadeghi, S., Rahbar, M.H., Iranpour, A., Salehi, A., Asadi, O. and Jafarian, S.R., 2018. Dobutamine-induced takotsubo cardiomyopathy: A systematic review of the literature and case report. Anatolian journal of cardiology, 19(6), p.412.
⁶³Saito, R., Takahashi, T., Noshita, N., Narisawa, A., Negi, K., Takei, K. and Kaneko, U., 2010. Takotsubo cardiomyopathy induced by dobutamine infusion during hypertensive therapy for symptomatic vasospasm after subarachnoid hemorrhage. Neurologia medico-chirurgica, 50(5), pp.393-395.
⁶⁴Abe, Y., Tamura, A. and Kadota, J., 2010. Prolonged cardiogenic shock caused by a high-dose intravenous administration of dopamine in a patient with takotsubo cardiomyopathy. International journal of cardiology, 141(1), pp.e1-e3. https://doi.org/10.1016/j.ijcard.2008.11.123

Dipyridamole, isoprenaline (isoproteranol), terlipressin.

⁶⁵Koh, AS, Kok, H, Chua, T, Keng, F. Takotsubo cardiomyopathy following dipyridamole pharmacologic stress. Ann Nucl Med. 2010;24(6):497–500.
⁶⁶Nakao, M, Kawaai, S, Nakamura, D, Tsunoda, A. Takotsubo cardiomyopathy during electrophysiological study with isoproterenol. Int J Cardiol. 2016;223:521–523.
⁶⁷Di Micoli, A., Buccione, D., Degli Esposti, D., Santi, V., Bastagli, L., Borghi, C., Bernardi, M. and Trevisani, F., 2011. Terlipressin infusion induces Tako-Tsubo syndrome in a cirrhotic man with hepato-renal syndrome. Internal and emergency medicine, 6(5), pp.437-440. https://doi.org/ DOI 10.1007/s11739-011-0534-6
⁶⁸Zdanowicz, J.A., Utz, A.C., Bernasconi, I., Geier, S., Corti, R. and Beinder, E., 2011. “Broken heart” after cesarean delivery. Case report and review of literature. Archives of Gynecology and Obstetrics, 283(4), pp.687-694.
⁶⁹Suzuki, T., Nemoto, C., Ikegami, Y., Yokokawa, T., Tsukada, Y., Abe, Y., Shimada, J., Takeishi, Y. and Tase, C., 2014. Development of takotsubo cardiomyopathy with severe pulmonary edema before a cesarean section. Journal of Anesthesia, 28(1), pp.121-124.
⁷⁰Crimi, E., Baggish, A., Leffert, L., Pian-Smith, M. C., Januzzi, J. L., & Jiang, Y. (2008). Acute reversible stress-induced cardiomyopathy associated with cesarean delivery under spinal anesthesia. Circulation, 117(23), 3052-3053.
⁷¹Kim, D.H., Bang, D.W. and Park, H.K., 2010. Atypical basal type takotsubo cardiomyopathy: MDCT findings correlated with echocardiography. International Journal of Cardiology, 141(2), pp.e28-e30.
⁷²Nanayakkara, S. and Cooke, J., 2016, May. Takotsubo cardiomyopathy associated with the administration of intranasal phenylephrine/lignocaine for epistaxis. In International Cardiovascular Forum Journal (Vol. 5).
 ⁷³Lee, A. and Nguyen, P., 2016. Takotsubo cardiomyopathy due to systemic absorption of intraocular phenylephrine. Heart, Lung and Circulation, 25(12), pp.e159-e161.
⁷⁴Syed, O.N., Heyer, E.J. and Connolly Jr, E.S., 2009. Takotsubo syndrome after carotid endarterectomy. Journal of Neurosurgical Anesthesiology, 21(2), pp.181-182.

Drugs used in the treatment of mental health conditions
Serotonin norepinephrine reuptake inhibitors (SNRIs)
⁷⁵Nelson, C. 2017. Serotonin-norepinephrine reuptake inhibitors (SNRIs): Pharmacology, administration, and side effects, UptoDate,viewed 31^st March 2019 < https://www.uptodate.com/contents/serotonin-norepinephrine-reuptake-inhibitors-snris-pharmacology-administration-and-side-effects>⁹⁶Goyal, S.K., Gera, C., Singla, M. and ⁷⁶Kumar, N., 2018. Desvenlafaxine overdose-induced toxic cardiomyopathy and acute left ventricular failure: A case report. Indian Journal of Psychological Medicine, 40(1), p.99.
https://doi.org/ 10.4103/IJPSYM.IJPSYM_397_17
⁷⁷Gurunathan, U., 2018. Takotsubo Cardiomyopathy and Intraoperative Cardiac Arrest: Is Desvenlafaxine a Contributing Factor? Journal of Cardiothoracic and Vascular Anesthesia, 32(1), pp.e16-e18. https://doi.org/ 10.1053/j.jvca.2017.08.031
⁷⁸Bergman, B.R., Reynolds, H.R., Skolnick, A.H. and Castillo, D., 2008. A case of apical ballooning cardiomyopathy associated with duloxetine. Annals of internal medicine, 149(3), pp.218-219.
⁷⁹Selke, K.J., Dhar, G. and Cohn, J.M., 2011. Takotsubo cardiomyopathy associated with titration of duloxetine. Texas Heart Institute Journal, 38(5), p.573. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3231522/
⁸⁰Rotondi, F., Manganelli, F., Carbone, G. and Stanco, G., 2011. ” Tako-tsubo” cardiomyopathy and duloxetine use. Southern medical journal, 104(5), pp.345-347.https://doi.org/ 10.1097/SMJ.0b013e318213f3e5
⁸¹Forman, M.B., Sutej, P.G. and Jackson, E.K., 2011. Hypertension, tachycardia, and reversible cardiomyopathy temporally associated with milnacipran use. Texas Heart Institute Journal, 38(6), p.714. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3233339/
⁸²Fangio, P., De Jonghe, B., Appéré-De-Vecchi, C., Lachérade, J.C., Terville, J.P., Outin, H. and Dagorn, J., 2007. Acute heart failure associated with venlafaxine poisoning. The American journal of emergency medicine, 25(2), p.210.https://doi.org/ 10.1016/j.ajem.2006.08.007
⁸³Christoph, M., Ebner, B., Stolte, D., Ibrahim, K., Kolschmann, S., Strasser, R.H. and Schön, S., 2010. Broken heart syndrome: Tako Tsubo cardiomyopathy associated with an overdose of the serotonin–norepinephrine reuptake inhibitor Venlafaxine. European Neuropsychopharmacology, 20(8), pp.594-597. https://doi.org/10.1016/j.euroneuro.2010.03.009
⁸⁴Daly, M.J., Harbinson, M.T., Dixon, L.J. and Spence, M.S., 2010. An unusual case of mid-ventricular Takotsubo cardiomyopathy. QJM: An International Journal of Medicine, 103(9), pp.695-696. https://doi.org/10.1093/qjmed/hcq008
⁸⁵Neil, C.J., Chong, C.R., Nguyen, T.H. and Horowitz, J.D., 2012. Occurrence of Tako-Tsubo cardiomyopathy in association with ingestion of serotonin/noradrenaline reuptake inhibitors. Heart, Lung and Circulation, 21(4), pp.203-205. https://doi.org/10.1016/j.hlc.2011.12.004
⁸⁶Vasudev, R., Rampal, U., Patel, H., Patel, K., Bikkina, M. and Shamoon, F., 2016. Selective serotonin–norepinephrine reuptake inhibitors-induced takotsubo cardiomyopathy. North American journal of medical sciences, 8(7), p.312. https://doi.org/ 10.4103/1947-2714.187153
⁸⁷Yamaguchi, H., Nagumo, K., Nakashima, T., Kinugawa, Y. and Kumaki, S., 2014. Life-threatening QT prolongation in a boy with attention-deficit/hyperactivity disorder on atomoxetine. European journal of pediatrics, 173(12), pp.1631-1634.
⁸⁸Naguy, A., Al-Mutairi, H. and Al-Tajali, A., 2016. Atomoxetine-related Takotsubo cardiomyopathy. Journal of Psychiatric Practice®, 22(3), pp.232-233.
⁸⁹De Roock, S., Beauloye, C., De Bauwer, I., Vancraynest, D., Gurne, O., Gerber, B. and Hantson, P., 2008. Tako-tsubo syndrome following nortriptyline overdose. Clinical Toxicology, 46(5), pp.475-478. https://doi.org/10.1080/15563650701519786
⁹⁰Kitami, M, Oizumi, H, Kish, SJ, Furukawa, Y. Takotsubo cardiomyopathy associated with lithium intoxication in bipolar disorder: a case report. J Clin Psychopharmacol. 2014;34(3):410–411.
⁹¹Narayanan, M.A., Haddad, T.M., Bansal, O., Baskaran, J., Azzouz, M.S., Akinapelli, A. and Esterbrooks, D.J., 2015. Acute cardiomyopathy precipitated by lithium: is there a direct toxic effect on cardiac myocytes?. The American Journal of Emergency Medicine, 33(9), pp.1330-e1.

Drugs used in the treatment of cancer

Chemotherapy agents

⁹²Desai, R., Abbas, S.A., Goyal, H., Durairaj, A., Fong, H.K., Hung, O., Sachdeva, R., Barac, A., Yusuf, S.W. and Kumar, G., 2019. Frequency of takotsubo cardiomyopathy in adult patients receiving chemotherapy (from a 5-year nationwide inpatient study). The American Journal of Cardiology, 123(4), pp.667-673.https://doi.org/10.1016/j.amjcard.2018.11.006
⁹³Balanescu, D.V., Liu, V.Y., Donisan, T., Agha, A.M., Lopez-Mattei, J.C., Giza, D.E., Iliescu, G.D., Palaskas, N., Kim, P.Y., Boone, D.L. and Yang, E.H., 2018. P1253 Clinical features and outcomes of patients with chemotherapy-induced Takotsubo stress cardiomyopathy. European Heart Journal, 39(suppl_1), pp.ehy565-P1253.https://doi-org/10.1093/eurheartj/ehy565.P1253
⁹⁴Sattler, K., El-Battrawy, I., Lang, S., Zhou, X., Schramm, K., Tülümen, E., Kronbach, F., Röger, S., Behnes, M., Kuschyk, J. and Borggrefe, M., 2017. Prevalence of cancer in Takotsubo cardiomyopathy: short and long-term outcome. International journal of cardiology, 238, pp.159-165.
⁹⁵Akhtar, S.S., Salim, K.P. and Bano, Z.A., 1993. Symptomatic cardiotoxicity with high-dose 5-fluorouracil infusion: a prospective study. Oncology, 50(6), pp.441-444. https://doi.org/10.1016/j.ijcard.2017.02.093
⁹⁶Gianni, M., Dentali, F. and Lonn, E., 2009. 5 flourouracil-induced apical ballooning syndrome: a case report. Blood Coagulation & Fibrinolysis, 20(4), pp.306-308.
⁹⁷Kobayashi, N., Hata, N., Yokoyama, S., Shinada, T., Shirakabe, A. and Mizuno, K., 2009. A case of Takotsubo cardiomyopathy during 5-fluorouracil treatment for rectal adenocarcinoma. Journal of Nippon Medical School, 76(1), pp.27-33.
⁹⁸Stewart, T., Pavlakis, N. and Ward, M., 2010. Cardiotoxicity with 5‐fluorouracil and capecitabine: more than just vasospastic angina. Internal medicine journal, 40(4), pp.303-307.
⁹⁹Basselin, C., Fontanges, T., Descotes, J., Chevalier, P., Bui‐Xuan, B., Feinard, G. and Timour, Q., 2011. 5‐Fluorouracil—Induced Tako‐Tsubo—Like Syndrome. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 31(2), pp.226-226.
¹⁰⁰Grunwald, M.R., Howie, L. and Diaz Jr, L.A., 2011. Takotsubo cardiomyopathy and fluorouracil: case report and review of the literature. Journal of Clinical Oncology, 30(2), pp.e11-e14.
¹⁰¹Radhakrishnan, V, Bakhshi, S. 5-Fluorouracil-induced acute dilated cardiomyopathy in a pediatric patient. J Pediatr Hematol Oncol. 2011;33(4):323.
¹⁰²Çalık, A.N., Çeliker, E., Velibey, Y., Çağdaş, M. and Güzelburç, Ö., 2012. Initial dose effect of 5-fluorouracil: rapidly improving severe, acute toxic myopericarditis. The American journal of emergency medicine, 30(1), pp.257-e1.
¹⁰³Lim, S.H.S., Wilson, S.M., Hunter, A., Hill, J. and Beale, P., 2013. Takotsubo cardiomyopathy and 5-fluorouracil: getting to the heart of the matter. Case reports in oncological medicine, 2013.
¹⁰⁴Ozturk, M.A., Ozveren, O., Cinar, V., Erdik, B. and Oyan, B., 2013. Takotsubo syndrome: an underdiagnosed complication of 5-fluorouracil mimicking acute myocardial infarction. Blood Coagulation & Fibrinolysis, 24(1), pp.90-94.
¹⁰⁵Goel, S., Sharma, A., Garg, A., Chandra, A. and Shetty, V., 2014. Chemotherapy induced Takotsubo cardiomyopathy. World Journal of Clinical Cases: WJCC, 2(10), p.565.
¹⁰⁶Knott, K., Starling, N., Rasheed, S., Foran, J., Cafferkey, C., Rosen, S., Nicholson, A., Baksi, J. and Lyon, A., 2014. A case of Takotsubo syndrome following 5-fluorouracil chemotherapy. International journal of cardiology, 177(2), pp.e65-e67.
¹⁰⁷Singh, S.B. and Harle, I.A., 2014. Takotsubo cardiomyopathy secondary in part to cancer-related pain crisis: a case report. Journal of pain and symptom management, 48(1), pp.137-142.
¹⁰⁸Abdelrahman, M., McCarthy, M.T., Yusof, H. and Osman, N., 2016. Successful capecitabine rechallenge following 5-fluorouracil-induced Takotsubo syndrome. Oxford medical case reports, 2016(3), pp.47-50.
¹⁰⁹De Pasquale, M.D., Mastronuzzi, A., De Sio, L., Serra, A., Grimaldi, C., Chinali, M. and Giordano, U., 2016. Transient global ventricular dysfunction in an adolescent affected by pancreatic adenocarcinoma. BMC pediatrics, 16(1), p.99.
¹¹⁰Fakhri, Y., Dalsgaard, M., Nielsen, D. and Madsen, P.L., 2016. 5-Fluorouracil-induced acute reversible heart failure not explained by coronary spasms, myocarditis or takotsubo: lessons from MRI. BMJ case reports, 2016, p.bcr2015213783.
¹¹¹Saif, M.W., Smith, M. and Maloney, A., 2016. The first case of severe takotsubo cardiomyopathy associated with 5-fluorouracil in a patient with abnormalities of both dihydropyrimidine dehydrogenase (DPYD) and thymidylate synthase (TYMS) genes. Cureus, 8(9)..
¹¹²Coen, M., Rigamonti, F., Roth, A. and Koessler, T., 2017. Chemotherapy-induced Takotsubo cardiomyopathy, a case report and review of the literature. BMC cancer, 17(1), p.394.
¹¹³Shekar, C. and Tigadi, S., 2018. 5-flurouracil induced takotsubo cardiomyopathy. Journal of the American College of Cardiology, 71(11 Supplement), p.A2431.
¹¹⁴Stewart, T., Pavlakis, N. and Ward, M., 2010. Cardiotoxicity with 5‐fluorouracil and capecitabine: more than just vasospastic angina. Internal medicine journal, 40(4), pp.303-307.
¹¹⁵Endo, A., Yoshida, Y., Nakashima, R., Takahashi, N. and Tanabe, K., 2013. Capecitabine induces both cardiomyopathy and multifocal cerebral leukoencephalopathy. International heart journal, 54(6), pp.417-420.
¹¹⁶Y-Hassan, S, Tornvall, P, Tornerud, M, Henareh, L. Capecitabine caused cardiogenic shock through induction of global takotsubo syndrome. Cardiovasc Revasc Med. 2013;14(1):57–61.
¹¹⁷Fontanella, C., Aita, M., Cinausero, M., Aprile, G., Baldin, M.G., Dusi, V., Lestuzzi, C., Fasola, G. and Puglisi, F., 2014. Capecitabine-induced cardiotoxicity: more evidence or clinical approaches to protect the patients’ heart?. OncoTargets and therapy, 7, p.1783.
¹¹⁸Klag, T., Cantara, G., Ong, P., Kaufmann, M., Sechtem, U. and Athanasiadis, A., 2014. Epicardial coronary artery spasm as cause of capecitabine-induced tako tsubo cardiomyopathy. Clinical Research in Cardiology, 103(3), pp.247-250.
¹¹⁹Qasem, A., Abdulhak, A.A.B., Aly, A. and Moormeier, J., 2016. Capecitabine-induced takotsubo cardiomyopathy: a case report and literature review. American journal of therapeutics, 23(5), pp.e1188-e1192.
¹²⁰Sakamoto, T., Endo, A., Ito, S., Okada, T., Watanabe, N. and Tanabe, K., 2016. Capecitabine Induced Takotsubo Cardiomyopathy. Journal of Cardiac Failure, 22(9), p.S220
¹²¹Coen, M., Rigamonti, F., Roth, A. and Koessler, T., 2017. Chemotherapy-induced Takotsubo cardiomyopathy, a case report and review of the literature. BMC cancer, 17(1), p.394.
¹²²Budnik, M., Kucharz, J., Wiechno, P., Demkow, T., Kochanowski, J., Górska, E. and Opolski, G., 2018. Chemotherapy-induced Takotsubo syndrome. Clinical Pulmonary Research, pp.19-29.
¹²³Sabharwal, S., Sharma, A., Manek, G. and Grover, P., 2018. A case of capecitabine-induced takotsubo cardiomyopathy. Chest, 154(4).
¹²⁴Franco, T.H., Khan, A., Joshi, V. and Thomas, B., 2008. Takotsubo cardiomyopathy in two men receiving bevacizumab for metastatic cancer. Therapeutics and clinical risk management, 4(6), p.1367.
¹²⁵ Kim, L., Karas, M. and Wong, S.C., 2008. Chemotherapy-induced takotsubo cardiomyopathy. The Journal of invasive cardiology, 20(12), pp.E338-40.
¹²⁶Geisler, B.P., Raad, R.A., Esaian, D., Sharon, E. and Schwartz, D.R., 2015. Apical ballooning and cardiomyopathy in a melanoma patient treated with ipilimumab: a case of takotsubo-like syndrome. Journal for immunotherapy of cancer, 3(1), p.4. https://doi.org/10.1186/s40425-015-0048-2
¹²⁷Ng, K.H., Dearden, C. and Gruber, P., 2015. Rituximab-induced Takotsubo syndrome: more cardiotoxic than it appears?. BMJ case reports, 2015, p.bcr2014208203.
¹²⁸Khanji, M, Nolan, S, Gwynne, S, Pudney, D, Ionescu, A. Tako-Tsubo syndrome after trastuzumab—an unusual complication of chemotherapy for breast cancer. Clin Oncol (R Coll Radiol). 2013;25(5):329.
¹²⁹Aguiar-Ricardo, I., Nunes-Ferreira, A., Roda, Â. and Bras-Rosario, L., 2019. Omalizumab induced Takotsubo syndrome: case report. European Heart Journal-Case Reports, 3(1), p.yty155.
¹³⁰Ovadia, D., Esquenazi, Y., Bucay, M. and Bachier, C.R., 2014. Association between takotsubo cardiomyopathy and axitinib: case report and review of the literature. Journal of Clinical Oncology, 33(1), pp.e1-e3.
¹³¹White, A.J., LaGerche, A., Toner, G.C. and Whitbourn, R.J., 2009. Apical ballooning syndrome during treatment with a vascular endothelial growth factor receptor antagonist. International journal of cardiology, 131(3), pp.e92-e94. https://doi.org/10.1016/j.ijcard.2007.07.066 (pazopanib)
¹³²Numico, G., Sicuro, M., Silvestris, N., Mozzicafreddo, A., Trogu, A., Malossi, A., Cristofano, A. and Thiebat, B., 2012. Takotsubo syndrome in a patient treated with sunitinib for renal cancer. Journal of Clinical Oncology, 30(24), pp.e218-e220.
¹³³Cevallos, J. and Lyon, A., 2018. Takotsubo Syndrome and Cancer. In Cancer and Cardiovascular Disease (pp. 45-54). Springer, Cham.
¹³⁴Bhakta, S, Flick, SM, Cooney, MM. Myocardial stunning following combined modality combretastatin-based chemotherapy: two case reports and review of the literature. Clin Cardiol. 2009;32(12):80–84.
¹³⁵ Khakoo, A.Y., Halushka, M.K., Rame, J.E., Rodriguez, E.R., Kasper, E.K. and Judge, D.P., 2005. Reversible cardiomyopathy caused by administration of interferon α. Nature Reviews Cardiology, 2(1), p.53.
¹³⁶Damodaran, S., Mrozek, E., Liebner, D. and Kendra, K., 2014. Focal takotsubo cardiomyopathy with high-dose interleukin-2 therapy for malignant melanoma. Journal of the National Comprehensive Cancer Network, 12(12), pp.1666-1670.
¹³⁷Coli, S., Pigazzani, F. and Gaibazzi, N., 2015. Midventricular Takotsubo cardiomyopathy after oxaliplatin infusion: an unreported side effect. Journal of Cardiovascular Medicine, 16(9), pp.646-649.
¹³⁸ Sundaravel, S., Alrifai, A., Kabach, M. and Ghumman, W., 2017. FOLFOX induced takotsubo cardiomyopathy treated with impella assist device. Case reports in cardiology, 2017.
¹³⁹Baumann, S., Huseynov, A., Goranova, D., Faust, M., Behnes, M., Nolte, F., Heidenreich, D., Hofmann, W.K., Borggrefe, M., Akin, I. and Klein, S., 2014. Takotsubo cardiomyopathy after systemic consolidation therapy with high-dose intravenous cytarabine in a patient with acute myeloid leukemia. Oncology research and treatment, 37(9), pp.487-490.
¹⁴⁰Goel, S., Sharma, A., Garg, A., Chandra, A. and Shetty, V., 2014. Chemotherapy induced Takotsubo cardiomyopathy. World Journal of Clinical Cases: WJCC, 2(10), p.565.
¹⁴¹ Malley, T. and Watson, E., 2016. A case of takotsubo cardiomyopathy after chemotherapy. Oxford medical case reports, 2016(4), pp.55-58.

Drugs used in obstetrics

¹⁴²Jeon, J.H., Her, S.H., Lee, J.M., Yoon, H.J., Chin, J.Y., Park, K.H., Won, K.Y., Jie, B.S., Park, Y.R. and Jin, S.W., 2007. A case of stress-induced cardiomyopathy related with the postpartum period. Korean Circulation Journal, 37(8), pp.388-392.
¹⁴³Citro, R., Pascotto, M., Provenza, G., Gregorio, G. and Bossone, E., 2010. Transient left ventricular ballooning (tako-tsubo cardiomyopathy) soon after intravenous ergonovine injection following caesarean delivery. International Journal of Cardiology, 138(2), pp.e31-34-34. https://doi.org/10.1016/j.ijcard.2008.06.041
¹⁴⁴Kim, S.Y., Yoon, J.H. and Lee, S.H., 2011. Takotsubo-like severe left ventricular dysfunction after cesarean delivery in a 28-year old woman. Korean Circulation Journal, 41(2), pp.101-104.
¹⁴⁵Keskin, A., Winkler, R., Mark, B., Kilkowski, A., Bauer, T., Koeth, O., Camci, S., Cornelius, B., Layer, G., Zeymer, U. and Zahn, R., 2010. Tako-tsubo cardiomyopathy after administration of ergometrine following elective caesarean delivery: a case report. Journal of Medical Case Reports, 4(1), p.280. https://doi.org/10.1186/1752-1947-4-280
¹⁴⁶Vital, M., Lebert, C., Reignier, J. and Ducarme, G., 2013. Peripartum cardiomyopathy vs. sulprostone-associated heart failure? A case report and analysis of the literature. Archives of Gynecology and Obstetrics, 288(6), pp.1423-1424.
¹⁴⁷Suzuki, T., Nemoto, C., Ikegami, Y., Yokokawa, T., Tsukada, Y., Abe, Y., Shimada, J., Takeishi, Y. and Tase, C., 2014. Development of takotsubo cardiomyopathy with severe pulmonary edema before a cesarean section. Journal of Anesthesia, 28(1), pp.121-124.
¹⁴⁸Courand, P.Y., Jenck, S., Cassar, E., David, E., Carrabin, N. and Lantelme, P., 2012. Tako-tsubo cardiomyopathy probably associated with administration of sulprostone following cesarean delivery. Revista Española de Cardiología, 65(08), pp.770-771.
¹⁴⁹Sato, A., Yagihara, N., Kodama, M., Mitsuma, W., Tachikawa, H., Ito, M., Hanawa, H. and Aizawa, Y., 2011. Takotsubo cardiomyopathy after delivery in an oestrogen-deficient patient. International journal of cardiology, 149(2), pp.e78-e79.
¹⁵⁰Petta R, Zullo F, Tipaldi A, Guida M. 2013. A “Broken heart” syndrome case after cesarean delivery. prevention and risk assessment. Translational Medicine@ UniSa; 7:29.
¹⁵¹Besnier E, Hubscher C, Doguet F, Bessou JP, Dureuil B. Extracorporeal membrane oxygenation support for tako-tsubo syndrome after urgent caesarean section. Ann Fr Anesth Reanim 2013; 32:704-6.
¹⁵²D’Amato, N., Colonna, P., Brindicci, P., Campagna, M.G., Petrillo, C., Cafarelli, A. and D’Agostino, C., 2008. Tako-Tsubo syndrome in a pregnant woman. European Journal of Echocardiography, 9(5), pp.700-703.
¹⁵³Bortnik M, Verdoia M, Schaffer A, Occhetta E, Marino P. Ventricular fibrillation as primary presentation of takotsubo cardiomyopathy after complicated cesarean delivery. World Journal of Cardiology 2012; 4:214.
¹⁵⁴Freitas, H.F.G., Renault, R., Ribeiro, E.S., Andrade, F.M., Brito Jr, F.S. and Velloso, L.G., 2011. Sudden cardiac arrest due to puerperal transient left ventricular apical ballooning syndrome. International journal of cardiology, 149(1), pp.e12-e13.
¹⁵⁵Kraft, K., Graf, M., Karch, M. and Felberbaum, R., 2017. Takotsubo syndrome after cardiopulmonary resuscitation during emergency cesarean delivery. Obstetrics & Gynecology, 129(3), pp.521-524.
¹⁵⁶Lee, N., Lee, K., Banta, J., D’Ambrosio, M., Hannallah, B., Benz, M. and Voudouris, A., 2017. Takotsubo Cardiomyopathy-Associated Ventricular Standstill in a Peripartum Patient. Journal of Molecular and Cellular Cardiology, 112, p.139.
¹⁵⁷Kucia, A.M., Dekker, G. and Arstall, M., 2015. Peripartum takotsubo cardiomyopathy. Journal of the American College of Cardiology, 65(10 Supplement), p.A926.
¹⁵⁸Bhaskar S, Shevlin M, Koumousidis A, Hunter A. 2013. Broken heart syndrome in a new mother with HELLP syndrome: A case report. OA Case Reports, 2(8):71. http://www.oapublishinglondon.com/images/article/pdf/1383005843.pdf
¹⁵⁹Jeong, H., Lee, S., Jeong, C., Lee, J., Jeong, S., Chung, S. and Yoo, K., 2011. Inverted takotsubo-like left ventricular dysfunction with pulmonary oedema developed after caesarean delivery complicated by massive haemorrhage in a severe preeclamptic parturient with a prolonged painful labour. Case Reports in Anesthesiology, 2011.
¹⁶⁰ Crimi, E., Baggish, A., Leffert, L., Pian-Smith, M.C., Januzzi, J.L. and Jiang, Y., 2008. Acute reversible stress-induced cardiomyopathy associated with cesarean delivery under spinal anesthesia. Circulation, 117(23), pp.3052-3053. https://doi.org/10.1161/CIRCULATIONAHA.107.744102
¹⁶¹Gnanavelu, G., Sathiakumar, D.B.D., Narasimhan, M.K. and Priya, M.S., 2014. Stress-induced cardiomyopathy following cesarean delivery under general anesthesia. The Journal of Obstetrics and Gynecology of India, 64(1), pp.19-21.
¹⁶²Ozpelit, E, Ozpelit, ME, Akdeniz, B, Goldeli, O. 2016. Ergotamine-induced takotsubo cardiomyopathy. Am J Ther, 23(2):597–600.
¹⁶³Minatoguchi, M., Itakura, A., Takagi, E., Nishibayashi, M., Kikuchi, M. and Ishihara, O., 2014. Takotsubo cardiomyopathy after cesarean: A case report and published work review of pregnancy‐related cases. Journal of Obstetrics and Gynaecology Research, 40(6), pp.1534-1539.
¹⁶⁴Lee, J. Y., Kwon, H. J., Park, S. W., & Lee, Y. M. (2017). Acute pulmonary edema caused by takotsubo cardiomyopathy in a pregnant woman undergoing transvaginal cervical cerclage: A case report. Medicine, 96(1).
¹⁶⁵Shoji, T., Takatori, E., Oyama, R., Kumagai, S., Fukushima, A., Yoshizaki, A. and Sugiyama, T., 2012. Tako-Tsubo cardiomyopathy caused immediately following cesarean section delivery of triplets: a case report. Gynecologic and obstetric investigation, 74(1), pp.84-88.
¹⁶⁶Niki, Y., Takasu, A., Sakakibara, K., Matsuzaki, Y., Tsuboi, H. and Minakuchi, K., 2003. A case report of postpartum pulmonary edema associated with long-term administration of ritodrine. Journal of the Japanese Society of Intensive Care Medicine, 10(3), pp.201-205

Asthma medications

¹⁶⁷Stanojevic, D.A., Alla, V.M., Lynch, J.D. and Hunter, C.B., 2010. Case of reverse takotsubo cardiomyopathy in status asthmaticus. Southern Medical Journal, 103(9), p.964.
¹⁶⁸Salahuddin, F.F., Sloane, P., Buescher, P., Agarunov, L. and Sreeramoju, D., 2013. A case of apical ballooning syndrome in a male with status asthmaticus; highlighting the role of B2 agonists in the pathophysiology of a reversible cardiomyopathy. Journal of Community Hospital Internal Medicine Perspectives, 3(2), p.20530.
¹⁶⁹Patel, B., Assad, D., Wiemann, C. and Zughaib, M., 2014. Repeated use of albuterol inhaler as a potential cause of Takotsubo cardiomyopathy. The American Journal of Case Reports, 15, p.221.
¹⁷⁰Marmoush, F.Y., Barbour, M.F., Noonan, T.E. and Al-Qadi, M.O., 2015. Takotsubo cardiomyopathy: a new perspective in Asthma. Case Reports in Cardiology, 2015.http://dx.doi.org/10.1155/2015/640795
¹⁷¹Sharrett, J, Surabhi, S, Philips, S, Morse, H. Fatal case of recurrent takotsubo cardiomyopathy presenting with cardiac arrest and variable ventricular involvement what role beta agonist and beta blockers? J S C Med Assoc. 2015;111(4):127–130.
¹⁷²Kamath, A.P., Shenoy, M., Kulandaisamy, S., Seneviratne, C., Kupfer, Y. and Chandar, P., 2016. Takotsubo Cardiomyopathy Associated With High Dose Albuterol, ATS Journals. Viewed online 11^th April 2019, https://www.atsjournals.org/doi/pdf/10.1164/ajrccm-conference.2016.193.1_MeetingAbstracts.A6960
¹⁷³Parsa, S.A., Khaheshi, I., Memaryan, M. and Naderian, M., 2016. Takotsubo cardiomyopathy following recurrent doses of albuterol due to asthma attack: a very rare case report. Future Cardiology, 12(6), pp.609-612.
¹⁷⁴Mendoza, I. and Novaro, G.M., 2012. Repeat recurrence of takotsubo cardiomyopathy related to inhaled beta-2-adrenoceptor agonists. World Journal of Cardiology, 4(6), p.211.
¹⁷⁵Venditti, F, Bellandi, B, Parodi, G. Fatal Tako-Tsubo cardiomyopathy recurrence after β2-agonist administration. Int J Cardiol. 2012;161(1):10–11.
¹⁷⁶Melao, F, Nunes, JP, Vasconcelos, M. Stress-induced cardiomyopathy associated with ipratropium bromide therapy in a patient with chronic obstructive pulmonary disease. Rev Port Cardiol. 2014;33(3):171–174.
¹⁷⁷Dakkak, M., 2016. Seizure, theophylline toxicity and Takotsubo cardiomyopathy (first report): case report. Reactions, 1583, pp.1052-9.
¹⁷⁸Khwaja, Y.H. and Tai, J.M., 2016. Takotsubo cardiomyopathy with use of salbutamol nebulisation and aminophylline infusion in a patient with acute asthma exacerbation. BMJ Case Reports, 2016, p.bcr2016217364.
¹⁷⁹Saeki, S., Matsuse, H., Nakata, H., Fukahori, S., Miyahara, Y. and Kohno, S., 2006. Case of bronchial asthma complicated with Takotsubo cardiomyopathy after frequent epinephrine medication. Nihon Kokyuki Gakkai zasshi= The Journal of the Japanese Respiratory Society, 44(10), pp.701-705.

Illicit drugs

¹⁸⁰Chokshi, SK, Moore, R, Pandian, NG, Isner, JM. 1989. Reversible cardiomyopathy associated with cocaine intoxication. Ann Intern Med, 111(12):1039–1040.
¹⁸¹Arora, S, Alfayoumi, F, Srinivasan, V. 2006. Transient left ventricular apical ballooning after cocaine use: is catecholamine cardiotoxicity the pathologic link? Mayo Clin Proc, 81(6):829–832.
¹⁸²Daka, MA, Khan, RS, Deppert, EJ. 2007. Transient left ventricular apical ballooning after a cocaine binge. J Invasive Cardiol, 19(12):378–380.
Butterfield, M, Riguzzi, C, Frenkel, O, Nagdev, A. 2015. Stimulant-related takotsubo cardiomyopathy. Am J Emerg Med, 33(3):1–3.
¹⁸³Sarkar, S, Arguelles, E, de Elia, C. 2013. Takotsubo cardiomyopathy presenting as a non-ST segment elevation myocardial infarction in the setting of cocaine use and asthma exacerbation. Int J Cardiol, 168(1):1–2.
¹⁸⁴Srikanth, S, Barua, R, Ambrose, J. Methamphetamine-associated acute left ventricular dysfunction: a variant of stress-induced cardiomyopathy. Cardiology. 2008;109(3):188–192.
¹⁸⁵Fulcher, J, Wilcox, I. Basal stress cardiomyopathy induced by exogenous catecholamines in younger adults. Int J Cardiol. 2013;168(6):158–160.
¹⁸⁶Al-Abri, S, Meier, KH, Colby, JM, Smollin, CG, Benowitz, NL. Cardiogenic shock after use of fluoroamphetamine confirmed with serum and urine levels. Clin Toxicol (Phila). 2014;52(10):1292–1295.
¹⁸⁷Alliu, S., Adejumo, A., Adegbala, O., Namana, V., Chetana, P., Yevgeniya, B., Hecht, M., Wolf, L., Kamholz, S., Hollander, G. and Shani, J., 2017. Association Between Cannabis Use and TakoTsubo Cardiomyopathy (TTC): Analysis from the NIS 2012-2014. Circulation Research, 121(suppl_1), pp.A209-A209.
¹⁸⁸Khalid, S., Khalid, A. and Maroo, P., 2018. Risk Factors and Management of Takotsubo Cardiomyopathy. Cureus, 10(5): e2626. https://doi.org/10.7759/cureus.2626

Withdrawal syndromes

¹⁸⁹Suzuki, K, Osada, N, Akasi, YJ. 2004. An atypical case of “Takotsubo cardiomyopathy” during alcohol withdrawal: abnormality in the transient left ventricular wall motion and a remarkable elevation in the ST segment. Intern Med, 43(4):300–305.
¹⁹⁰Alexandre, J, Benouda, L, Champ-Rigot, L, Labombarda, F. 2011. Takotsubo cardiomyopathy triggered by alcohol withdrawal. Drug Alcohol Rev, 30(4):434–437.
¹⁹¹Stout, B.J., Hoshide, R. and Vincent, D.S., 2012. Takotsubo cardiomyopathy in the setting of acute alcohol withdrawal. Hawai’i Journal of Medicine & Public Health, 71(7), p.193.
¹⁹²Lemesle, F, Lemesle, F, Nicola, W, Pierre Jonville-Bera, A. 2010. First case of stress cardiomyopathy as a result of methadone withdrawal secondary to drug-drug interaction. Am J Emerg Med, 28(3):385–386.
¹⁹³Saiful, FB, Lafferty, J, Jun, CH. 2011. Takotsubo cardiomyopathy due to iatrogenic methadone withdrawal. Rev Cardiovasc Med, 12(3):164–167.
¹⁹⁴Rivera, JM, Locketz, AJ, Fritz, KD. “Broken heart syndrome” after separation (from OxyContin). Mayo Clinic Proceedings. 2006;81(6):825–828.
¹⁹⁵Sarcon, A, Ghadri, JR, Wong, G, Luscher, TF, Templin, C, Amsterdam, E. Takotsubo cardiomyopathy associated with opiate withdrawal. QJM. 2014;107(4):301–302.
¹⁹⁶Pizon, AF, Lovecchio, F. Reversible cardiomyopathy complicating intrathecal baclofen withdrawal: a case report. J Med Toxicol. 2007;3(4):187–189.
¹⁹⁷Kireyev, D, Poh, KK. Reversible electrocardiogram changes and cardiomyopathy secondary to baclofen withdrawal syndrome. Am Heart Hosp J. 2010;8(1):52–54.
¹⁹⁸Maruyama, S, Nomura, Y, Fukushige, T. 2006. Suspected takotsubo cardiomyopathy caused by withdrawal of buprenorphine in a child. Circ J, 70(4):509–511.
¹⁹⁹Jefic, D, Koul, D, Boguszewski, A, Martini, W. Transient left ventricular apical ballooning syndrome caused by abrupt metoprolol withdrawal. Int J Cardiol. 2008;131(1):35–37.
²⁰⁰Tomcsanyi, J, Javor, K, Arabadzisz, H, Zsoldos, A, Wagner, V, Sarman, B. Takotsubo cardiomyopathy: a novel beta-adrenergic blocker withdrawal syndrome. Orv Hetil. 2013;154(7):267–271.

Other drugs

²⁰¹Dziewierz, A, Olszanecka, A, Wilinski, J. Inverted takotsubo cardiomyopathy in a patient with essential thrombocythemia exposed to anagrelide and phentermine. Int J Cardiol. 2012;160(2):31–32.
²⁰²Proietti, R., Rognoni, A., Ardizzone, F., Maccio, S., Santagostino, A. and Rognoni, G., 2009. Atypical Takotsubo syndrome during anagrelide therapy. Journal of Cardiovascular Medicine, 10(7), pp.546-549.
²⁰³Sandhu, G, Servetnyk, Z, Croitor, S, Herzog, E. Atropine aggravates signs and symptoms of takotsubocardiomyopathy. Am J Emerg Med. 2010;28(2):255–257.
²⁰⁴Y-Hassan, S, Jernberg, T. Bromocriptine-induced coronary spasm caused acute coronary syndrome, which triggered its own clinical twin—takotsubo syndrome. Cardiology. 2011;119(1):1–6.
²⁰⁵McAllister, R.K., 2014, April. Stress-induced (takotsubo) cardiomyopathy following thoracic epidural steroid injection for postherpetic neuralgia. In Baylor University Medical Center Proceedings (Vol. 27, No. 2, pp. 120-121). Taylor & Francis.
²⁰⁶ Schussler, J.M., 2014. Takotsubo cardiomyopathy following epidural steroid injection: yet another way to break the heart. Proceedings (Baylor University. Medical Center), 27(2), p.122.
²⁰⁷Baldacci, F., Vergallo, A., Del Dotto, P., Ulivi, M., Palombo, C., Casolo, G., Tomei, G. and Bonuccelli, U., 2014. Occurrence of Takotsubo syndrome in a patient with Parkinson’s disease after entacapone add-on. Parkinsonism & related disorders, 20(11), pp.1313-1314.
²⁰⁸Gabriel, L., Chenu, P., Guédès, A., Dangoisse, V., Marchandise, B., Blommaert, D., Jamart, J., De Roy, L. and Schroeder, E., 2011. A possible association between takotsubo cardiomyopathy and treatment with flecainide. International journal of cardiology, 147(1), pp.173-175.
²⁰⁹Santoro, F., Ieva, R., Ferraretti, A., Carpagnano, G., Pappalardo, I., De Gennaro, L., Di Biase, M. and Brunetti, N.D., 2013. Tako-tsubo cardiomyopathy after influenza vaccination. International journal of cardiology, 167(2), pp.e51-e52.
²¹⁰Kwon, S.A., Yang, J.H., Kim, M.K., Park, S.W., Kim, S.H., Park, K.H. and Park, W.J., 2010. A case of Takotsubo cardiomyopathy in a patient with iatrogenic thyrotoxicosis. International journal of cardiology, 145(3), pp.e111-e113.
²¹¹Eliades, M., El-Maouche, D., Choudhary, C., Zinsmeister, B. and Burman, K.D., 2014. Takotsubo cardiomyopathy associated with thyrotoxicosis: a case report and review of the literature. Thyroid, 24(2), pp.383-389.
²¹²Balsa, A.M., Ferreira, A.R., Alves, M. and Guimarães, J., 2017. Takotsubo cardiomyopathy associated with levothyroxine over-replacement. European endocrinology, 13(1), p.30.
²¹³Maricic, L., Makarovic, S., Selthofer-Relatic, K., Jelic, K. and Steiner, R., 2015. Takotsubo cardiomyopathy caused iatrogenic thyrotoxicosis. Case Reports in Internal Medicine, 2(2), pp.82-84. 230
²¹⁴Sacco, A, Morici, N, Belli, O, Bossi, I, Mafrici, A, Klugmann, S. Tako-Tsubo like syndrome triggered by meperidine. Med J Malaysia. 2011;66(5):520–521.
²¹⁵Ramanath, VS, Andrus, BW, Szot, CR, Kaplan, AV, Robb, JF. Takotsubo cardiomyopathy after midodrine therapy. Tex Heart Inst J. 2012;39(1):158–159.
²¹⁶Placci, A., Sella, G., Bellanti, G. and Margheri, M., 2015. Anabolic androgenic steroid-induced Takotsubo cardiomyopathy. BMJ case reports, 2015, p.bcr2014209089.
²¹⁷Rojas-Marte, G., John, J., Sadiq, A., Moskovits, N., Saunders, P. and Shani, J., 2015. Medication-induced Takotsubo Cardiomyopathy presenting with cardiogenic shock—utility of extracorporeal membrane oxygenation (ECMO): case report and review of the literature. Cardiovascular Revascularization Medicine, 16(1), pp.47-51.
²¹⁸Kocaoglu, I., Gökaslan, S., Karagöz, A., Sahin, D., Ucar, Ö. and Aydogdu, S., 2012. Zolmitriptan-induced acute myocardial infarction. Cardiology journal, 19(1), pp.76-78.
²¹⁹Garg, J, Aronow, WS, Devabhaktuni, S, Ahmad, H. Takotsubo syndrome (or apical ballooning syndrome) secondary to zolmitriptan. Am J Ther. 2015;22(2):52–56.